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TEM.NASDAQ
Tempus AI, Inc. Common Stock
Healthcare · Health Information Services

AI-enabled precision medicine company combining diagnostics, clinical data, and analytics to improve oncology and broader care decisions.

HQ: United StatesListed: United States

AI Consensus

On this page, you will be able to compare multi-agent consensus ratings, forecast paths, AI price targets, expected return, fundamentals, analyst disagreement, risks, and the investment thesis across short- and long-term horizons.

AI Consensus Investment Thesis

Tempus AI, Inc. Common Stock (TEM) Stock Forecast and AI Rating

Deep analysis published Returns refreshed
1-Year and 5-Year Forecast Outlook

Forecast targets and rating

Final recommendation

Hold & Monitor

Model signals are balanced; wait for clearer evidence.

2027

1-Year

NEUTRAL

$61

+9.3%
2031

5-Year

NEUTRAL

$124

+122.0%

Latest flagship insight

Why the Market Misprices This Biological Data Moat Under Restrictive Rates

There is sharp divergence across reports regarding this asset's valuation sustainability, though high consensus exists on its formidable clinical data moat. While geopolitical decoupling acts as a primary driver, persistent cash burn and high leverage remain the central risks threatening near-term performance under restrictive monetary conditions.

LATEST PUBLISHED DEEP ANALYSIS BY iPULSE AI ENGINE

This is the latest published deep-analysis batch. Audit previous forecasts in full transparency

Warren Buffett (Value Purist) advisor portraitSuperintelligence (Anthropologist) advisor portraitRay Dalio (Strategist) advisor portraitMachiavelli (Insider) advisor portraitElon Musk (Visionary) advisor portraitMichael Burry (Vulture) advisor portraitJ.P. Morgan (Titan) advisor portraitSherlock Holmes (Whistleblower) advisor portrait

Warren Buffett (Value Purist), Superintelligence (Anthropologist), Ray Dalio (Strategist), Machiavelli (Insider), Elon Musk (Visionary), Michael Burry (Vulture), J.P. Morgan (Titan), Sherlock Holmes (Whistleblower). Some archetypes run in multiple modes, resulting in 12 advisors total.

Research support only. We don't give financial advice.

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Executive Summary

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Expert Language
Explained Simply

Interactive forecast chart

Figure: Five-year interactive consensus forecast for Tempus AI, Inc. Common Stock, including the advisor-disagreement range and benchmark comparison. Sign in, verify your email, and use the required subscription to explore the chart.

This asset presents a highly polarized setup, balancing an unassailable clinical-genomic against severe leverage and . The core thesis hinges on the rapid mix-shift toward high-margin data licensing and AI modeling, which is expected to drive and push the company toward neutrality by late 2027 or 2028. While the geopolitical tailwinds of the structurally insulate domestic , the restrictive and elevated discount rates will continue to compress valuation multiples, demanding flawless operational execution.

Key insights

  • High-margin data licensing and AI platform scaling act as the primary engines for .
  • The serves as a powerful regulatory barrier, redirecting domestic biopharma R&D spend away from foreign competitors.
  • Persistent and a heavy create significant refinancing risks under a higher-for-longer interest rate environment.
  • Sharp divergence exists between bulls focusing on software-like and bears highlighting capital-intensive diagnostic lab realities.
  • Achieving positive remains the critical catalyst to eliminate fears and trigger institutional re-rating.
  • Strategic risk includes potential regulatory data privacy crackdowns or technological by generalized foundation models.
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AI Consensus
AI Forecasts
Company Profile

Alpha Gap & Repricing Catalysts

Where does the current market narrative diverge from our AI Forecasts—and what could close the gap?

Market Narrative

What does the market currently expect? The general market narrative views the asset as a high-octane growth story positioned at the intersection of and precision medicine. Retail investors and sell-side analysts are heavily focused on the company's rapid top-line revenue growth and massive , often treating the path to profitability as a guaranteed outcome of software-scale leverage. However, a parallel, more skeptical crowd narrative treats the stock as a speculative, cash-burning hybrid that is highly vulnerable to elevated interest rates. This camp views the business as a traditional, capital-intensive diagnostic laboratory that has inflated its valuation by attaching a trendy label to its operations.

Alpha Gap

What is the biggest difference between market expectations and our AI forecasts? The core information gap lies in the market's misclassification of the company's business model and strategic moat. While the crowd evaluates the asset either as a standard diagnostic lab or a cyclical software stock vulnerable to , the recognizes that the physical diagnostics division is actually a subsidized customer acquisition funnel designed to build an unassailable, multi-modal clinical dataset. This proprietary data is structurally insulated from economic downturns and heavily protected by domestic policy mandates like the . As US pharmaceutical companies are forced to onshore their data pipelines, this dataset transitions from a discretionary tool to a mandatory national security asset. The market is mispricing the inevitability of the that will occur when high-margin data licensing outpaces physical lab costs.

Repricing Catalyst

What could make the market recognize and close that gap? The primary catalyst to force convergence is the company achieving structurally positive , which would definitively dismantle the bearish thesis of terminal . This financial inflection is expected to be driven by the high-margin Data and Applications segment outgrowing the physical diagnostics division in absolute gross profit contribution. Additionally, securing a landmark multi-billion-dollar enterprise partnership with a major pharmaceutical giant or obtaining significant pricing uplifts from regulatory approvals will accelerate this transition. Once positive cash generation is established, the market will be forced to re-rate the asset from a speculative biotech hybrid to a high-margin enterprise software platform.

Sentiment and Timing

What do sentiment, volatility, and the market-recognition cycle suggest about the thesis timing?

Greed / Fear
Mixed
Volatility
High Erratic
Cycle position
Growing Awareness

Sentiment is highly polarized. Bulls emphasize accelerating momentum and growing awareness of the , while bears point to a potential reversal or overshoot, citing heavy insider selling, short-seller allegations, and the hostile high-rate environment as key drivers of near-term volatility.

Macro Regime Fit

Does the current market environment support the thesis? The presents a highly bifurcated setup for the asset. On one hand, the restrictive monetary environment, characterized by higher-for-longer interest rates and tight liquidity, acts as a severe headwind for valuation multiples, heavily discounting the company's long-duration future cash flows and exposing its leveraged . On the other hand, the geopolitical regime of supply-chain decoupling and domestic protectionism, exemplified by the , serves as a massive structural tailwind. This political environment forces US biopharma capital into secure, domestic data ecosystems, effectively shielding the company's fundamental business operations from broader macroeconomic deterioration.

Advisor Disagreement

What do our AI Advisors disagree about most? The primary disagreement across reports centers on the and the timeline to profitability. Bullish perspectives emphasize the rapid growth of the high-margin data segment and argue that will quickly extinguish the , justifying a premium . Conversely, bearish reports focus on the capital-intensive nature of the physical diagnostic labs, arguing that the business is being mispriced as a company. There is also significant debate regarding the severity of regulatory privacy liabilities and whether insider selling signals structural weakness or routine diversification.

Base-Case Forces

Near-certain positive forces

Top Drivers / Tailwinds

Near-certain forces that support the investment thesis. These forces are treated as part of the base case (more than 60% probability of occurrence). Impact columns are specific to this asset class.

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Top Drivers / Tailwinds with asset-specific estimated impacts and thesis rationale
Driver / TailwindCategoryEst. stock-price impactEst. earnings impactWhy it matters
Sovereign Biological Competitive Positioning+45%+50%The company's un-replicable multimodal clinical and genomic dataset forms a powerful . As AI models shift toward precision medicine, pharmaceutical companies rely heavily on this structured data for drug discovery. The further strengthens this moat by isolating foreign competitors, forcing domestic biopharma to route R&D through secure domestic infrastructure, ensuring long-term and customer lock-in.
Operational Efficiency+35%+45%The rapid scaling of the high-margin Data and Applications segment is driving a structural mix-shift. have expanded toward 70%, demonstrating classic technology platform . As high fixed R&D and initial data-ingestion costs are amortized against a growing base, the transition from operating losses to positive is expected to accelerate.
and Product InnovationInnovation And Product+25%+30%The launch of advanced platforms like 'Lens' shifts the company from static data licensing to active, autonomous AI modeling for clinical trials and biomarker discovery. This innovation allows biopharma clients to compress drug development timelines, enabling the company to command premium, high-margin revenues and deeply integrate into client workflows, which drives long-term contract value.
Regulatory TailwindRegulatory+20%+25%Federal legislation targeting Chinese genomic competitors creates a protected domestic market. US biopharma and research institutions are structurally rotating capital away from foreign service providers toward compliant domestic platforms. This regulatory shift acts as a state-sponsored demand funnel, securing domestic and over the long term, shielding the company from low-cost overseas competition.

Near-certain negative forces

Top Frictions / Headwinds

Near-certain forces that could slow, cap, or damage the thesis. These forces are treated as part of the base case (more than 60% probability of occurrence). Impact columns are specific to this asset class.

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Top Frictions / Headwinds with asset-specific estimated impacts and thesis rationale
Friction / HeadwindCategoryEst. stock-price impactEst. earnings impactWhy it matters
Persistent and Capital Allocation-35%-25%Despite strong top-line growth, the company continues to run a deep deficit. Operating in a restrictive with elevated capital costs makes this a severe liability. If the path to profitability is delayed, the company faces punitive or highly to sustain operations, which limits near-term equity upside.
Warsh Rate Regime Macroeconomic And Macrofinancial-25%-5.0%Persistent higher-for-longer interest rates act as a relentless gravitational drag on long-duration growth equities. Because the bulk of the company's lies in cash flows projected years into the future, elevated discount rates mechanically compress the , leaving no for operational execution errors and limiting .
Regulatory and Privacy Litigation LiabilitiesRegulatory-20%-15%The acquisition of genetic testing assets has exposed the company to class-action lawsuits under state privacy acts and regulatory scrutiny over unauthorized data monetization. These legal challenges threaten the fundamental legality of the secondary data-licensing engine, potentially imposing massive and restricting data-sharing pipelines, which could severely damage the core business model.
Egregious Stock-Based Compensation and Management And Governance-15%-20%Heavy reliance on stock-based compensation to attract talent acts as a persistent drag on per-share value. This aggressive masks true underlying operating costs and frustrates institutional investors seeking . Synchronized insider selling further signals a potential lack of internal conviction in the current valuation, creating a persistent overhang on the stock price.

What Could Break or Accelerate the Thesis

Plausible downside scenarios

Tail Risks

Tail yet plausible downside scenarios selected for their highest potential impact.

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Tail risks with plausibility, asset-specific potential impact, exposure category, and scenario rationale
Tail scenarioChance of OccurringStock Price ImpactExposure categoryWhy plausible / what changes
Existential Liquidity and Refinancing Crisis30%-55%Capital AllocationIf the company burns through its cash reserves before achieving , and credit markets remain hostile, it may face a toxic refinancing event. This would force highly issuances at trough valuations, permanently destroying shareholder value and forcing a severe downward repricing of the equity.
Open-Source Biological Model Displacement20%-45%Innovation And ProductA consortium of tech giants or open-source advocates could release a free, highly capable biological foundation model that bypasses the company's proprietary structuring moat. This technological shift would commoditize genomic AI capabilities, destroying the company's and software margins, reducing the platform to a low-margin data broker.

Plausible upside scenarios

Tail Opportunities

Tail yet plausible upside scenarios selected for their highest potential impact.

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Tail opportunities with plausibility, asset-specific potential impact, exposure category, and scenario rationale
Tail scenarioChance of OccurringStock Price ImpactExposure categoryWhy plausible / what changes
Strategic Mega-Pharma Acquisition20%+45%Competitive PositioningA top-tier pharmaceutical giant or technology hyperscaler, desperate to secure a monopoly on proprietary clinical-genomic data for AI drug discovery, could launch a buyout at a massive premium. This would instantly capitalize the of the and bypass public-market duration discounting, delivering an immediate windfall to existing shareholders.
FDA AI-Diagnostic Mandate15%+35%RegulatoryRegulatory bodies could formally mandate the company's advanced AI-driven genomic profiling as a prerequisite for administering high-cost targeted therapies. This would transform the platform from a competitive advantage into a statutory requirement, locking in utility-like recurring revenues across the healthcare system and driving massive, un-modeled revenue growth.

Company Financial Analysis

Tempus AI, Inc. Common Stock Earnings and Financials Analysis by AI

Financial figures available as of Jul 05, 2026. Only filings and source records available by this analysis date are included.

Earnings and financials

The company is experiencing explosive sales growth, with annual revenues climbing rapidly, driven by its high-margin data and software segment. However, its bottom-line profits remain deeply negative, with substantial net losses and ongoing cash burn. Analysts agree that the company's future depends on its ability to transition from a cash-burning business to a self-sustaining, profitable enterprise. The main point of disagreement is how quickly this transition will happen. Optimistic views suggest that as the high-margin software business grows, it will easily cover the fixed costs of the physical testing labs, leading to profitability by 2028. Skeptics, however, warn that the heavy costs of running physical laboratories and high stock-based compensation will keep the company unprofitable for much longer, making the stock highly risky in a high-interest-rate environment where investors demand real earnings over future promises.

Revenue, earnings, and cash flow

The table compares up to five fiscal years of revenue, net income, and free cash flow available to this analysis.

Revenue, net income, and free cash flow history
Fiscal yearRevenueNet incomeFree cash flow
2025USD 1.3BUSD -245MUSD -239.1M
2024USD 693.4MUSD -705.8MUSD -211.2M
2023USD 531.8MUSD -214.1MUSD -248.9M
2022USD 320.7MUSD -289.8MUSD -186.6M
2021USD 257.9MUSD -259.2MUSD -223.8M

Valuation context: historical P/E

The table compares up to five fiscal years of point-in-time valuation evidence available to this analysis.

Historical price-to-earnings ratios
Fiscal yearP/EEarnings basisCurrency basisTicker / reporting
2025--TTMLoss-makingUSD / USD
2024--TTMLoss-makingUSD / USD
2023--TTMUnavailableUSD / USD
2022--AnnualUnavailableUSD / USD
2021--AnnualUnavailableUSD / USD

P/E uses historical market capitalization and earnings known at each period. Cross-currency observations are normalized to USD using point-in-time FX rates.

Profitability and margins

The company's profit margins show a striking contrast between its raw product costs and its overall business expenses. Gross margins, which measure the basic profitability of its services, have expanded beautifully to around seventy percent. This indicates that the core data-licensing business is highly profitable and has strong pricing power. However, operating and net margins remain deeply negative because of massive spending on research, sales, and executive stock compensation. The consensus is that margins will improve as high-margin software sales become a larger part of the business. However, opinions clash on whether the company can trim its heavy overhead costs. Bulls believe operating margins will turn positive within a few years as the business scales, while bears argue that the high costs of running physical labs and generous executive pay will permanently weigh down profitability, making the current high valuation hard to justify.

The table compares up to five fiscal years of operating income and reported profitability margins.

Operating income and margin history
Fiscal yearOperating incomeOperating marginNet margin
2025USD -238.6M-18.8%-19.3%
2024USD -691.1M-99.7%-101.8%
2023USD -196.1M-36.9%-40.3%
2022USD -265.4M-82.8%-90.4%
2021USD -243.7M-94.5%-100.5%

Balance sheet and leverage

The company's balance sheet presents a mix of near-term safety and long-term risk. On the positive side, it holds a substantial cash cushion of over six hundred million dollars, which provides a temporary buffer to fund its ongoing operations. However, the company also carries a massive debt load of over one billion dollars, resulting in a very high debt-to-equity ratio. Analysts agree that this heavy leverage makes the company highly vulnerable. If the company cannot stop burning cash before its current reserves run out, it will be forced to borrow more money at high interest rates or issue new shares, which would dilute the value of existing investments. While some believe the cash buffer is plenty of runway to reach profitability, others view the high debt as a ticking clock that leaves no room for operational mistakes or economic downturns.

The table compares up to five fiscal years of debt, liquidity, net cash or debt, and current-ratio evidence.

Balance sheet leverage and liquidity history
Fiscal yearTotal debtCash + short-term investmentsNet cash / (debt)Current ratio
2025USD 1.3BUSD 755MUSD 722.3M net debt3.13x
2024USD 468.1MUSD 448.3MUSD 127.1M net debt2.29x
2023USD 488.1MUSD 197.6MUSD 322.4M net debt1.51x
2022USD 433MUSD 302.9MUSD 130.1M net debt2.52x
2021USD 238.9MUSD 277.7MUSD 38.7M net cash3.52x

Net debt below zero is displayed as net cash. Current ratio is current assets divided by current liabilities.

Capex and investment intensity

The company requires heavy spending to build and maintain its competitive edge, but the nature of this spending is a point of debate. On one hand, it operates physical, high-tech laboratories and invests heavily in research and development to gather and organize patient data. Optimists view this heavy upfront spending as a smart, long-term investment that builds an unassailable database, which can eventually be licensed to drug companies at almost zero ongoing cost. They note that capital spending as a percentage of revenue is actually declining, showing increased efficiency. On the other hand, critics argue that this high investment intensity is a permanent burden rather than a one-time cost. They warn that keeping up with rapid advancements in artificial intelligence and genetic sequencing will force the company to continuously spend massive amounts on technology, draining cash and delaying the timeline to positive cash flow.

The table compares up to five fiscal years of capital expenditure and research-and-development investment.

Capital expenditure and research and development history
Fiscal yearCapital expenditureR&D spend
2025USD 21MUSD 146.1M
2024USD 22.1MUSD 316.8M
2023USD 34.6MUSD 185.5M
2022USD 18.4MUSD 162.3M
2021USD 11.8MUSD 128.4M

Quarterly Forecast Scenarios

Tempus AI, Inc. Common Stock Quarterly Forecast Scenarios

One row per forecast quarter. Asset scenario targets are shown in USD; benchmark values are shown in USD.

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Quarterly Bear Case Stock Price, Base Case Stock Price, Bull Case Stock Price, and S&P 500 benchmark forecasts for Tempus AI, Inc. Common Stock.
TimelineBear Case Stock Price (USD)Base Case Stock Price (USD)Bull Case Stock Price (USD)S&P 500 benchmark (USD)
$48.22$57.56$69.31$736.09
$40.98$58.29$74.86$724.14
$34.84$59.96$82.34$713.57
$29.61$60.85$78.22$723.38
$27.59$61.92$87.61$716.61
$22.62$66.39$100.75$738.34
$23.76$69.82$108.81$746.91
$24.71$71.36$100.11$771.93
$18.53$74.01$110.12$782.73
$21.31$80.42$126.64$807.31
$19.18$84.36$139.30$822.72
$20.71$86.72$146.26$846.10
$21.13$89.87$137.49$852.53
$22.18$96.62$156.71$882.91
$21.07$100.72$166.31$900.46
$21.49$104.89$174.62$922.67
$20.85$104.95$183.66$935.91
$22.10$112.55$198.35$952.30
$22.10$117.22$208.27$976.28
$22.10$123.55$220.76$1,002

Research Provenance

References & Context

This Tempus AI, Inc. Common Stock consensus analysis combines structured market evidence with independent AI-agent forecasts. External references below are limited to sources recorded by the researcher agents for this forecast batch.

Primary analysis inputs

Independent AI Advisor panel

AI Advisors
12
AI Researchers
7
AI Thinkers
5

Context retained with this Consensus

The same public-safe market, global-event, and fundamental context supplied to the AI Advisor panel.

03

Global context snapshot

2025 Full-Year Global Market and World-Events Context

Download Archived Snapshot

Coverage 2025-01-01 to 2025-12-31 · Knowledge cutoff 2025-12-31

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Words
12.8K words
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90.8K characters

This full-year context package covers the principal geopolitical, economic, monetary-policy, technology, trade, energy, and institutional developments that shaped global markets during 2025. It gives the forecasting model a chronological account of major world events together with their likely transmission into growth, inflation, interest rates, supply chains, commodities, currencies, public markets, and sector-level investment conditions.

The package also includes monthly and quarterly macroeconomic and cross-asset reference tables spanning US and international growth, central-bank policy, sovereign yields, major equity indices, foreign exchange, energy, industrial and precious metals, and digital assets. Quarterly and full-year high-impact summaries are integrated; monthly quantitative series remain working values pending final audit, and that qualification is part of the preserved context.

Top 3 market shifts from 2025 Full-Year Global Market and World-Events Context
Top 3 Market Shifts From FileDateStatus
DeepSeek shock and AI economics reset2025-01-27OPEN ENDED TREND
US tariff regime escalation and trade-system rupture2025-02-01ACTIVE POLICY REGIME
Federal Reserve easing cycle after a prolonged hold2025-09-17ACTIVE POLICY REGIME

2026 Year-to-Date Global Market Context through 2026-05-31

Download Archived Snapshot

Coverage 2026-01-01 to 2026-05-31 · Knowledge cutoff 2026-05-31

File size
78K bytes
Words
10.9K words
Characters
78K characters

This year-to-date package described the geopolitical, macroeconomic, monetary-policy, technology, trade, energy, and cross-asset developments available through the batch knowledge cutoff of 2026-05-31.

It supplied dated market and policy context, including rates, sovereign yields, equities, foreign exchange, energy, metals, and digital assets, for the forecast generation workflow.

Top 3 market shifts from 2026 Year-to-Date Global Market Context through 2026-05-31
Top 3 Market Shifts From FileDateStatus
The Iran and Strait of Hormuz conflict shocked energy markets2026-02-28STARTED AND ONGOING
U.S. monetary policy entered the Warsh transition2026-01-30STARTED AND ACTIVE POLICY TRANSITION
Agentic AI and infrastructure spending kept expanding2026-01-01OPEN ENDED
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Fundamental context

Income statement

34 fields

costOfRevenue · currency_symbol · date · depreciationAndAmortization · +30 more fields

Balance sheet

64 fields

accountsPayable · accumulatedAmortization · accumulatedDepreciation · accumulatedOtherComprehensiveIncome · +60 more fields

Cash flow

32 fields

beginPeriodCashFlow · capitalExpenditures · cashAndCashEquivalentsChanges · cashFlowsOtherOperating · +28 more fields

Outstanding shares

4 fields

date · dateFormatted · shares · sharesMln

annual: 2020-01-01–2026-01-01, 7 periods; quarterly: 2023-06-30–2026-03-31, 12 periods

Currencies cited: USD (quote USD; primary reporting USD; converted/valuation USD).